Searchable abstracts of presentations at key conferences in endocrinology

ea0078p36 | Gonadal, DSD and Reproduction | BSPED2021

Neuroblastoma with concurrent X chromosome monosomy, a coincidence or an association?

S. Baranowski Elizabeth , Harding Eleanor , Gatz Susanne A. , McCarthy Liam , Chandran Harish , Godber Caroline , Denvir Louise , Turnbull Jenny , Idkowiak Jan , Randell Tabitha , Mohamed Zainaba

Background: Turner’s syndrome (TS) affects 25-50 per 100,000 females. Germinal cell tumour risk is described for TS with Y-chromosome presence (12%) and gonadal dysgenesis (15-35%) but other cancer risk is less well described. Neuroblastoma accounts for 6% of UK childhood cancer registrations, is the commonest cancer diagnosed in the first year of life and the most common extra-cranial solid tumour in childhood. It carries a UK incidence of 10.9 cases/million children. Pr...